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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP6
All Species:
19.09
Human Site:
S200
Identified Species:
46.67
UniProt:
Q16828
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16828
NP_001937.2
381
42320
S200
D
S
D
G
S
P
L
S
N
S
Q
P
S
F
P
Chimpanzee
Pan troglodytes
XP_526209
468
50775
P287
E
S
D
G
S
P
V
P
S
S
Q
P
A
F
P
Rhesus Macaque
Macaca mulatta
XP_001091142
368
40570
P187
E
S
D
G
S
P
V
P
S
S
Q
P
A
F
P
Dog
Lupus familis
XP_852241
381
42285
S200
D
S
D
G
S
P
L
S
N
S
Q
P
S
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBB1
381
42389
S200
D
S
D
G
S
P
L
S
N
S
Q
P
S
F
P
Rat
Rattus norvegicus
Q64346
381
42300
S200
D
S
D
G
S
P
L
S
N
S
Q
P
S
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506331
383
42666
P202
E
S
D
G
S
P
I
P
N
N
Q
P
A
F
P
Chicken
Gallus gallus
Q9PW71
375
41034
D199
A
A
R
R
D
M
L
D
A
L
G
I
T
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001163824
383
42813
S200
D
S
D
G
S
P
L
S
N
P
Q
P
S
F
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794377
403
44845
T178
T
T
L
V
Q
A
E
T
P
L
D
N
R
Y
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
70
99.7
N.A.
98.1
98.6
N.A.
71
37.5
N.A.
N.A.
80.4
N.A.
N.A.
N.A.
45.4
Protein Similarity:
100
70.3
83.4
100
N.A.
98.9
99.4
N.A.
86.6
53.8
N.A.
N.A.
88.7
N.A.
N.A.
N.A.
59.3
P-Site Identity:
100
66.6
66.6
100
N.A.
100
100
N.A.
66.6
6.6
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
93.3
20
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
0
0
10
0
0
0
30
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
80
0
10
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
30
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% F
% Gly:
0
0
0
80
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
60
0
0
20
0
0
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
60
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
80
0
30
10
10
0
80
0
0
90
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
80
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
80
0
0
80
0
0
50
20
60
0
0
50
0
0
% S
% Thr:
10
10
0
0
0
0
0
10
0
0
0
0
10
0
0
% T
% Val:
0
0
0
10
0
0
20
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _